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Recently, scaffolds made of electrospun fibers have aroused interest due to their similarity to the ECM, and high porosity.

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European Journal of Investigation in Health, Psychology and Education (EJIHPE).

International Journal of Environmental Research and Public Health (IJERPH).

International Journal of Turbomachinery, Propulsion and Power (IJTPP).

Journal of Open Innovation: Technology, Market, and Complexity (JOItmC).

Journal of Otorhinolaryngology, Hearing and Balance Medicine (OHBM).

Journal of Theoretical and Applied Electronic Commerce Research (JTAER).

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Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive-age women.

PCOS is characterized by hyperandrogenism and ovulatory dysfunction.

Women with PCOS have a high prevalence of obesity, insulin resistance (IR), increased blood pressure (BP), and activation of the renin angiotensin system (RAS).

We hypothesized that hyperandrogenemia upregulates renal sodium-glucose cotransporter-2 (SGLT2) expression and that the SGLT2 inhibitor Empagliflozin ameliorates cardiometabolic complications in a hyperandrogenemic PCOS model.

Empagliflozin attenuated androgen-mediated increases in fat mass, plasma leptin, intra-renal RAS, and BP but failed to decrease plasma insulin, HbA1c, or albuminuria.

In summary, SGLT2 inhibition proved beneficial in adiposity and BP reduction in the PCOS model; however, additional therapies may.

In summary, SGLT2 inhibition proved beneficial in adiposity and BP reduction in the PCOS model; however, additional therapies may be needed to improve IR and renal injury.

Bone tissue engineering is a rapidly developing, minimally invasive technique for regenerating lost bone with the aid of biomaterial scaffolds that mimic the structure and function of the extracellular matrix (ECM).

Recently, scaffolds made of electrospun fibers have aroused interest due to their.

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